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Effect of pulsatile stretch on unfolded protein response in a new model of the pulmonary hypertensive vascular wall

Persistent pulmonary hypertension of the newborn (PPHN) is characterized by hypoxemia and arterial remodeling. Dynamic stretch and recoil of the arterial wall during pulsation (in normal conduit arteries, stretch 20% above diastolic diameter) maintains homeostasis; a static arterial wall is associat...

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Detalles Bibliográficos
Autores principales: Hinton, Martha, Eltayeb, Elwasila, Ghavami, Saeid, Dakshinamurti, Shyamala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326203/
https://www.ncbi.nlm.nih.gov/pubmed/34368469
http://dx.doi.org/10.1016/j.bbrep.2021.101080