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Effect of pulsatile stretch on unfolded protein response in a new model of the pulmonary hypertensive vascular wall
Persistent pulmonary hypertension of the newborn (PPHN) is characterized by hypoxemia and arterial remodeling. Dynamic stretch and recoil of the arterial wall during pulsation (in normal conduit arteries, stretch 20% above diastolic diameter) maintains homeostasis; a static arterial wall is associat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326203/ https://www.ncbi.nlm.nih.gov/pubmed/34368469 http://dx.doi.org/10.1016/j.bbrep.2021.101080 |