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Transcriptional regulation of CYP19 by cohesin-mediated chromosome tethering in human granulosa cells
Human CYP19 spans a region of chromosome 15 of approximately 130 kb and encodes aromatase, an enzyme required for estrogen synthesis. In the human granulosa cell-line KGN, there are seven open chromatin regions within the CYP19 locus. In this study, we demonstrate that two of these regions ~40 kb up...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326343/ https://www.ncbi.nlm.nih.gov/pubmed/34368471 http://dx.doi.org/10.1016/j.bbrep.2021.101086 |