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Resveratrol-induced Sirt1 phosphorylation by LKB1 mediates mitochondrial metabolism
The NAD(+)-dependent deacetylase Sirt1 has been implicated in the prevention of many age-related diseases, including cancer, type 2 diabetes, and cardiovascular disease. Resveratrol, a plant polyphenol, exhibits antiaging, antitumor, and vascular protection effects by activating Sirt1. However, the...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326426/ https://www.ncbi.nlm.nih.gov/pubmed/34216621 http://dx.doi.org/10.1016/j.jbc.2021.100929 |