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Resveratrol-induced Sirt1 phosphorylation by LKB1 mediates mitochondrial metabolism

The NAD(+)-dependent deacetylase Sirt1 has been implicated in the prevention of many age-related diseases, including cancer, type 2 diabetes, and cardiovascular disease. Resveratrol, a plant polyphenol, exhibits antiaging, antitumor, and vascular protection effects by activating Sirt1. However, the...

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Detalles Bibliográficos
Autores principales:	Huang, Yuanyuan, Lu, Jianlin, Zhan, Li, Wang, Ming, Shi, Ronghua, Yuan, Xiao, Gao, Xinjiao, Liu, Xing, Zang, Jianye, Liu, Wei, Yao, Xuebiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326426/ https://www.ncbi.nlm.nih.gov/pubmed/34216621 http://dx.doi.org/10.1016/j.jbc.2021.100929

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