P-Rex1 Cooperates With TGFβR2 to Drive Lung Fibroblast Migration in Pulmonary Fibrosis

Pulmonary fibrosis is a kind of interstitial lung disease with progressive pulmonary scar formation, leading to irreversible loss of lung functions. The TGF-β1/Smad signaling pathway plays a key role in fibrogenic processes. It is associated with the increased synthesis of extracellular matrix, enha...

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Detalles Bibliográficos
Autores principales: Liang, Qing, Chang, Yanhua, Liu, Jing, Yu, Yan, Qiu, Wancheng, Li, Jiajia, Yang, Xu, Sun, Guangchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326510/
https://www.ncbi.nlm.nih.gov/pubmed/34349645
http://dx.doi.org/10.3389/fphar.2021.678733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326510/
https://www.ncbi.nlm.nih.gov/pubmed/34349645
http://dx.doi.org/10.3389/fphar.2021.678733

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