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P-Rex1 Cooperates With TGFβR2 to Drive Lung Fibroblast Migration in Pulmonary Fibrosis
Pulmonary fibrosis is a kind of interstitial lung disease with progressive pulmonary scar formation, leading to irreversible loss of lung functions. The TGF-β1/Smad signaling pathway plays a key role in fibrogenic processes. It is associated with the increased synthesis of extracellular matrix, enha...
Autores principales: | Liang, Qing, Chang, Yanhua, Liu, Jing, Yu, Yan, Qiu, Wancheng, Li, Jiajia, Yang, Xu, Sun, Guangchun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326510/ https://www.ncbi.nlm.nih.gov/pubmed/34349645 http://dx.doi.org/10.3389/fphar.2021.678733 |
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