Icariin Ameliorates Diabetic Renal Tubulointerstitial Fibrosis by Restoring Autophagy via Regulation of the miR-192-5p/GLP-1R Pathway

Tubulointerstitial fibrosis is one of the most common pathological features of diabetic nephropathy. Autophagy, an intracellular mechanism to remove damaged or dysfunctional cell parts and maintain metabolic homeostasis, is inhibited in diabetic neuropathy. Icariin is a traditional Chinese medicine...

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Detalles Bibliográficos
Autores principales: Jia, Zhirong, Wang, Kaiwei, Zhang, Yameng, Duan, Yalei, Xiao, Kang, Liu, Shuo, Ding, Xuansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326523/
https://www.ncbi.nlm.nih.gov/pubmed/34349660
http://dx.doi.org/10.3389/fphar.2021.720387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326523/
https://www.ncbi.nlm.nih.gov/pubmed/34349660
http://dx.doi.org/10.3389/fphar.2021.720387

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