Membrane Binding of α-Synuclein Stimulates Expansion of SNARE-Dependent Fusion Pore

SNARE-dependent membrane fusion is essential for neurotransmitter release at the synapse. Recently, α-synuclein has emerged as an important regulator for membrane fusion. Misfolded α-synuclein oligomers are potent fusion inhibitors. However, the function of normal α-synuclein has been elusive. Here,...

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Detalles Bibliográficos
Autores principales: Khounlo, Ryan, Hawk, Brenden J. D., Khu, Tung-Mei, Yoo, Gyeongji, Lee, Nam Ki, Pierson, Josh, Shin, Yeon-Kyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326570/
https://www.ncbi.nlm.nih.gov/pubmed/34350173
http://dx.doi.org/10.3389/fcell.2021.663431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326570/
https://www.ncbi.nlm.nih.gov/pubmed/34350173
http://dx.doi.org/10.3389/fcell.2021.663431

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