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Membrane Binding of α-Synuclein Stimulates Expansion of SNARE-Dependent Fusion Pore
SNARE-dependent membrane fusion is essential for neurotransmitter release at the synapse. Recently, α-synuclein has emerged as an important regulator for membrane fusion. Misfolded α-synuclein oligomers are potent fusion inhibitors. However, the function of normal α-synuclein has been elusive. Here,...
Autores principales: | Khounlo, Ryan, Hawk, Brenden J. D., Khu, Tung-Mei, Yoo, Gyeongji, Lee, Nam Ki, Pierson, Josh, Shin, Yeon-Kyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326570/ https://www.ncbi.nlm.nih.gov/pubmed/34350173 http://dx.doi.org/10.3389/fcell.2021.663431 |
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