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Binding of Tetracyclines to Acinetobacter baumannii TetR Involves Two Arginines as Specificity Determinants

Acinetobacter baumannii is an important nosocomial pathogen that requires thoughtful consideration in the antibiotic prescription strategy due to its multidrug resistant phenotype. Tetracycline antibiotics have recently been re-administered as part of the combination antimicrobial regimens to treat...

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Detalles Bibliográficos
Autores principales: Sumyk, Manuela, Himpich, Stephanie, Foong, Wuen Ee, Herrmann, Andrea, Pos, Klaas M., Tam, Heng-Keat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326586/
https://www.ncbi.nlm.nih.gov/pubmed/34349752
http://dx.doi.org/10.3389/fmicb.2021.711158