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CPI-637 as a Potential Bifunctional Latency-Reversing Agent That Targets Both the BRD4 and TIP60 Proteins
The failure of highly active antiretroviral therapy (HAART) has been largely responsible for the existence of latent human immunodeficiency virus type 1 (HIV-1) reservoirs. The “shock and kill” strategy was confirmed to reactivate HIV-1 latent reservoirs by latency-reversing agents (LRAs) for accele...
Autores principales: | Zheng, Tengyi, Chen, Pei, Huang, Yifan, Qiu, Jiayin, Zhou, Chenliang, Wu, Ziyao, Li, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326664/ https://www.ncbi.nlm.nih.gov/pubmed/34350133 http://dx.doi.org/10.3389/fcimb.2021.686035 |
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