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Increased circulating levels of angiotensin-(1–7) in severely ill COVID-19 patients

This letter reports an unexpected increase of the ACE2 product angiotensin-(1–7) and a parallel decrease of its substrate angiotensin II, suggesting a dysregulation of the renin–angiotensin system towards angiotensin-(1–7) formation in #COVID19 patients https://bit.ly/3xFXuTU

Detalles Bibliográficos
Autores principales: Valle Martins, Ana Luiza, da Silva, Filipe Alex, Bolais-Ramos, Lucas, de Oliveira, Gisele Capanema, Ribeiro, Renata Cunha, Pereira, Danilo Augusto Alves, Annoni, Filippo, Diniz, Mirella Monique Lana, Silva, Thuanny Granato Fonseca, Zivianni, Bruna, Cardoso, Alexandre Carvalho, Martins, Juliana Carvalho, Motta-Santos, Daisy, Campagnole-Santos, Maria José, Taccone, Fabio Silvio, Verano-Braga, Thiago, Santos, Robson Augusto Souza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326714/
https://www.ncbi.nlm.nih.gov/pubmed/34350288
http://dx.doi.org/10.1183/23120541.00114-2021