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Increased circulating levels of angiotensin-(1–7) in severely ill COVID-19 patients
This letter reports an unexpected increase of the ACE2 product angiotensin-(1–7) and a parallel decrease of its substrate angiotensin II, suggesting a dysregulation of the renin–angiotensin system towards angiotensin-(1–7) formation in #COVID19 patients https://bit.ly/3xFXuTU
| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
European Respiratory Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326714/ https://www.ncbi.nlm.nih.gov/pubmed/34350288 http://dx.doi.org/10.1183/23120541.00114-2021 |
| _version_ | 1783731894897082368 |
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| author | Valle Martins, Ana Luiza da Silva, Filipe Alex Bolais-Ramos, Lucas de Oliveira, Gisele Capanema Ribeiro, Renata Cunha Pereira, Danilo Augusto Alves Annoni, Filippo Diniz, Mirella Monique Lana Silva, Thuanny Granato Fonseca Zivianni, Bruna Cardoso, Alexandre Carvalho Martins, Juliana Carvalho Motta-Santos, Daisy Campagnole-Santos, Maria José Taccone, Fabio Silvio Verano-Braga, Thiago Santos, Robson Augusto Souza |
| author_facet | Valle Martins, Ana Luiza da Silva, Filipe Alex Bolais-Ramos, Lucas de Oliveira, Gisele Capanema Ribeiro, Renata Cunha Pereira, Danilo Augusto Alves Annoni, Filippo Diniz, Mirella Monique Lana Silva, Thuanny Granato Fonseca Zivianni, Bruna Cardoso, Alexandre Carvalho Martins, Juliana Carvalho Motta-Santos, Daisy Campagnole-Santos, Maria José Taccone, Fabio Silvio Verano-Braga, Thiago Santos, Robson Augusto Souza |
| author_sort | Valle Martins, Ana Luiza |
| collection | PubMed |
| description | This letter reports an unexpected increase of the ACE2 product angiotensin-(1–7) and a parallel decrease of its substrate angiotensin II, suggesting a dysregulation of the renin–angiotensin system towards angiotensin-(1–7) formation in #COVID19 patients https://bit.ly/3xFXuTU |
| format | Online Article Text |
| id | pubmed-8326714 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | European Respiratory Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-83267142021-08-03 Increased circulating levels of angiotensin-(1–7) in severely ill COVID-19 patients Valle Martins, Ana Luiza da Silva, Filipe Alex Bolais-Ramos, Lucas de Oliveira, Gisele Capanema Ribeiro, Renata Cunha Pereira, Danilo Augusto Alves Annoni, Filippo Diniz, Mirella Monique Lana Silva, Thuanny Granato Fonseca Zivianni, Bruna Cardoso, Alexandre Carvalho Martins, Juliana Carvalho Motta-Santos, Daisy Campagnole-Santos, Maria José Taccone, Fabio Silvio Verano-Braga, Thiago Santos, Robson Augusto Souza ERJ Open Res Research Letters This letter reports an unexpected increase of the ACE2 product angiotensin-(1–7) and a parallel decrease of its substrate angiotensin II, suggesting a dysregulation of the renin–angiotensin system towards angiotensin-(1–7) formation in #COVID19 patients https://bit.ly/3xFXuTU European Respiratory Society 2021-08-02 /pmc/articles/PMC8326714/ /pubmed/34350288 http://dx.doi.org/10.1183/23120541.00114-2021 Text en Copyright ©The authors 2021 https://creativecommons.org/licenses/by-nc/4.0/This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contact permissions@ersnet.org (mailto:permissions@ersnet.org) |
| spellingShingle | Research Letters Valle Martins, Ana Luiza da Silva, Filipe Alex Bolais-Ramos, Lucas de Oliveira, Gisele Capanema Ribeiro, Renata Cunha Pereira, Danilo Augusto Alves Annoni, Filippo Diniz, Mirella Monique Lana Silva, Thuanny Granato Fonseca Zivianni, Bruna Cardoso, Alexandre Carvalho Martins, Juliana Carvalho Motta-Santos, Daisy Campagnole-Santos, Maria José Taccone, Fabio Silvio Verano-Braga, Thiago Santos, Robson Augusto Souza Increased circulating levels of angiotensin-(1–7) in severely ill COVID-19 patients |
| title | Increased circulating levels of angiotensin-(1–7) in severely ill COVID-19 patients |
| title_full | Increased circulating levels of angiotensin-(1–7) in severely ill COVID-19 patients |
| title_fullStr | Increased circulating levels of angiotensin-(1–7) in severely ill COVID-19 patients |
| title_full_unstemmed | Increased circulating levels of angiotensin-(1–7) in severely ill COVID-19 patients |
| title_short | Increased circulating levels of angiotensin-(1–7) in severely ill COVID-19 patients |
| title_sort | increased circulating levels of angiotensin-(1–7) in severely ill covid-19 patients |
| topic | Research Letters |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326714/ https://www.ncbi.nlm.nih.gov/pubmed/34350288 http://dx.doi.org/10.1183/23120541.00114-2021 |
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