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Diet-dependent natriuretic peptide receptor C expression in adipose tissue is mediated by PPARγ via long-range distal enhancers

The cardiac natriuretic peptides (NPs) are well established as regulators of blood pressure and fluid volume, but they also stimulate adipocyte lipolysis and control the gene program of nonshivering thermogenesis in brown adipose tissue. The NP “clearance” receptor C (NPRC) functions to clear NPs fr...

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Detalles Bibliográficos
Autores principales: Shi, Fubiao, Simandi, Zoltan, Nagy, Laszlo, Collins, Sheila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326739/
https://www.ncbi.nlm.nih.gov/pubmed/34245781
http://dx.doi.org/10.1016/j.jbc.2021.100941