A Small Molecule Inhibitor of Pex3–Pex19 Interaction Disrupts Glycosome Biogenesis and Causes Lethality in Trypanosoma brucei

Trypanosomatid parasites, including Trypanosoma and Leishmania, are infectious zoonotic agents for a number of severe diseases such as African sleeping sickness and American trypanosomiasis (Chagas disease) that affect millions of people, mostly in the emergent world. The glycosome is a specialized...

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Detalles Bibliográficos
Autores principales: Banerjee, Hiren, LaPointe, Paul, Eitzen, Gary, Rachubinski, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326762/
https://www.ncbi.nlm.nih.gov/pubmed/34350186
http://dx.doi.org/10.3389/fcell.2021.703603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326762/
https://www.ncbi.nlm.nih.gov/pubmed/34350186
http://dx.doi.org/10.3389/fcell.2021.703603

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