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A mechanism linking perinatal 2,3,7,8 tetrachlorodibenzo-p-dioxin exposure to lower urinary tract dysfunction in adulthood

Benign prostatic hyperplasia/lower urinary tract dysfunction (LUTD) affects nearly all men. Symptoms typically present in the fifth or sixth decade and progressively worsen over the remainder of life. Here, we identify a surprising origin of this disease that traces back to the intrauterine environm...

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Detalles Bibliográficos
Autores principales: Turco, Anne E., Oakes, Steven R., Keil Stietz, Kimberly P., Dunham, Cheryl L., Joseph, Diya B., Chathurvedula, Thrishna S., Girardi, Nicholas M., Schneider, Andrew J., Gawdzik, Joseph, Sheftel, Celeste M., Wang, Peiqing, Wang, Zunyi, Bjorling, Dale E., Ricke, William A., Tang, Weiping, Hernandez, Laura L., Keast, Janet R., Bonev, Adrian D., Grimes, Matthew D., Strand, Douglas W., Tykocki, Nathan R., Tanguay, Robyn L., Peterson, Richard E., Vezina, Chad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326766/
https://www.ncbi.nlm.nih.gov/pubmed/34318329
http://dx.doi.org/10.1242/dmm.049068