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IMbrave 151: a randomized phase II trial of atezolizumab combined with bevacizumab and chemotherapy in patients with advanced biliary tract cancer

BACKGROUND: Biliary tract cancers (BTCs) are heterogenous, highly aggressive tumors that harbor a dismal prognosis for which more effective treatments are needed. The role of cancer immunotherapy in BTC remains to be characterized. The tumor microenvironment (TME) of BTC is highly immunosuppressed a...

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Detalles Bibliográficos
Autores principales: Hack, Stephen P., Verret, Wendy, Mulla, Sohail, Liu, Bo, Wang, Yulei, Macarulla, Teresa, Ren, Zhenggang, El-Khoueiry, Anthony B., Zhu, Andrew X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326820/
https://www.ncbi.nlm.nih.gov/pubmed/34377158
http://dx.doi.org/10.1177/17588359211036544