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Pioglitazone Ameliorates Renal Ischemia-Reperfusion Injury via Inhibition of NF-κB Activation and Inflammation in Rats

Renal ischemia-reperfusion injury (IRI) is considered as a major cause of acute kidney injury. In this study, we investigated the role of the NF-κB signaling pathway and inflammation in the amelioration of renal IRI using pioglitazone. Sprague–Dawley (SD) rats were subjected to bilateral renal arter...

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Detalles Bibliográficos
Autores principales: Zou, Gaode, Zhou, Zhiyu, Xi, Xiaoqing, Huang, Ruizhen, Hu, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326914/
https://www.ncbi.nlm.nih.gov/pubmed/34349671
http://dx.doi.org/10.3389/fphys.2021.707344