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Relationship Between Amyloid-β Deposition and Blood–Brain Barrier Dysfunction in Alzheimer’s Disease

Amyloid-β (Aβ) is the predominant pathologic protein in Alzheimer’s disease (AD). The production and deposition of Aβ are important factors affecting AD progression and prognosis. The deposition of neurotoxic Aβ contributes to damage of the blood–brain barrier. However, the BBB is also crucial in ma...

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Detalles Bibliográficos
Autores principales: Wang, Dong, Chen, Fanglian, Han, Zhaoli, Yin, Zhenyu, Ge, Xintong, Lei, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326917/
https://www.ncbi.nlm.nih.gov/pubmed/34349624
http://dx.doi.org/10.3389/fncel.2021.695479