Cargando…

The Structural E/I Balance Constrains the Early Development of Cortical Network Activity

Neocortical networks have a characteristic constant ratio in the number of glutamatergic projection neurons (PN) and GABAergic interneurons (IN), and deviations in this ratio are often associated with developmental neuropathologies. Cultured networks with defined cellular content allowed us to ask i...

Descripción completa

Detalles Bibliográficos
Autores principales: Xing, Wenxi, de Lima, Ana Dolabela, Voigt, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8326976/
https://www.ncbi.nlm.nih.gov/pubmed/34349623
http://dx.doi.org/10.3389/fncel.2021.687306