PEGylated AdipoRon derivatives improve glucose and lipid metabolism under insulinopenic and high-fat diet conditions

The pleiotropic actions of adiponectin in improving cell survival and metabolism have motivated the development of small-molecule therapeutic agents for treating diabetes and lipotoxicity. AdipoRon is a synthetic agonist of the adiponectin receptors, yet is limited by its poor solubility and bioavai...

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Detalles Bibliográficos
Autores principales: Onodera, Toshiharu, Ghazvini Zadeh, Ebrahim, Xu, Peng, Gordillo, Ruth, Guo, Zheng, Joffin, Nolwenn, Yu, Biao, Scherer, Philipp E., Li, Wen-hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327158/
https://www.ncbi.nlm.nih.gov/pubmed/34214600
http://dx.doi.org/10.1016/j.jlr.2021.100095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327158/
https://www.ncbi.nlm.nih.gov/pubmed/34214600
http://dx.doi.org/10.1016/j.jlr.2021.100095

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