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Heart Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 Gene Expression Associated With Male Sex and Salt-Sensitive Hypertension in the Dahl Rat

Angiotensin-converting enzyme 2 (ACE 2) in the heart including its sex dependency in the hypertensive heart, has not been much studied compared to ACE. In the present study, we used the Dahl salt-sensitive rat exposed to fructose and salt to model a hypertensive phenotype in males, females, and ovar...

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Detalles Bibliográficos
Autores principales: Ytrehus, Kirsti, Ludvigsen, Stian, Mancusi, Costantino, Gerdts, Eva, de Simone, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327162/
https://www.ncbi.nlm.nih.gov/pubmed/34349662
http://dx.doi.org/10.3389/fphys.2021.663819