Differential cardiotoxic electrocardiographic response to doxorubicin treatment in conscious versus anesthetized mice

INTRODUCTION: Doxorubicin (DOX), an anticancer drug used in chemotherapy, causes significant cardiotoxicity. This study aimed to investigate the effects of DOX on mouse cardiac electrophysiology, in conscious versus anesthetized state. METHODS: Male and female C57BL/6 mice were injected with saline,...

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Detalles Bibliográficos
Autores principales: Warhol, Anna, George, Sharon A., Obaid, Sofian N., Efimova, Tatiana, Efimov, Igor R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327163/
https://www.ncbi.nlm.nih.gov/pubmed/34337891
http://dx.doi.org/10.14814/phy2.14987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327163/
https://www.ncbi.nlm.nih.gov/pubmed/34337891
http://dx.doi.org/10.14814/phy2.14987

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