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Differential cardiotoxic electrocardiographic response to doxorubicin treatment in conscious versus anesthetized mice
INTRODUCTION: Doxorubicin (DOX), an anticancer drug used in chemotherapy, causes significant cardiotoxicity. This study aimed to investigate the effects of DOX on mouse cardiac electrophysiology, in conscious versus anesthetized state. METHODS: Male and female C57BL/6 mice were injected with saline,...
Autores principales: | Warhol, Anna, George, Sharon A., Obaid, Sofian N., Efimova, Tatiana, Efimov, Igor R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327163/ https://www.ncbi.nlm.nih.gov/pubmed/34337891 http://dx.doi.org/10.14814/phy2.14987 |
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