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Mitochondrial Structure and Polarity in Dendrites and the Axon Initial Segment Are Regulated by Homeostatic Plasticity and Dysregulated in Fragile X Syndrome

Mitochondrial dysfunction has long been overlooked in neurodevelopmental disorders, but recent studies have provided new links to genetic forms of autism, including Rett syndrome and fragile X syndrome (FXS). Mitochondria show plasticity in morphology and function in response to neuronal activity, a...

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Detalles Bibliográficos
Autores principales: Bülow, Pernille, Wenner, Peter A., Faundez, Victor, Bassell, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327182/
https://www.ncbi.nlm.nih.gov/pubmed/34350185
http://dx.doi.org/10.3389/fcell.2021.702020