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scRNA sequencing uncovers a TCF4-dependent transcription factor network regulating commissure development in mouse

Transcription factor 4 (TCF4) is a crucial regulator of neurodevelopment and has been linked to the pathogenesis of autism, intellectual disability and schizophrenia. As a class I bHLH transcription factor (TF), it is assumed that TCF4 exerts its neurodevelopmental functions through dimerization wit...

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Detalles Bibliográficos
Autores principales: Wittmann, Marie-Theres, Katada, Sayako, Sock, Elisabeth, Kirchner, Philipp, Ekici, Arif B., Wegner, Michael, Nakashima, Kinichi, Lie, Dieter Chichung, Reis, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327186/
https://www.ncbi.nlm.nih.gov/pubmed/34184026
http://dx.doi.org/10.1242/dev.196022