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Effects of shikonin on the development of ovarian follicles and female germline stem cells

OBJECTIVE: To investigate the effects and potential mechanism of action of shikonin (SHK) on the development of ovarian follicles and female germline stem cells (FGSCs). METHODS: Female Kunming adult mice were administered SHK (0, 20 and 50 mg/kg) by oral gavage. Cultures of FGSCs were treated with...

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Detalles Bibliográficos
Autores principales: Ma, Shu-Xin, Tang, Li-Bo, Chen, Zhi-Hang, Wei, Min-Li, Tang, Zi-Juan, Zheng, Yue-Hui, Zong, Guo, Li, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327240/
https://www.ncbi.nlm.nih.gov/pubmed/34325571
http://dx.doi.org/10.1177/03000605211029461