Low tolerance for transcriptional variation at cohesin genes is accompanied by functional links to disease-relevant pathways

Background: The cohesin complex plays an essential role in genome organisation and cell division. A full complement of the cohesin complex and its regulators is important for normal development, since heterozygous mutations in genes encoding these components can be sufficient to produce a disease ph...

Descripción completa

Detalles Bibliográficos
Autores principales: Schierding, William, Horsfield, Julia A, O'Sullivan, Justin M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Functional Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327319/
https://www.ncbi.nlm.nih.gov/pubmed/32917770
http://dx.doi.org/10.1136/jmedgenet-2020-107095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327319/
https://www.ncbi.nlm.nih.gov/pubmed/32917770
http://dx.doi.org/10.1136/jmedgenet-2020-107095

Ejemplares similares