Regulation of a pentameric ligand-gated ion channel by a semiconserved cationic lipid-binding site

Pentameric ligand-gated ion channels (pLGICs) are crucial mediators of electrochemical signal transduction in various organisms from bacteria to humans. Lipids play an important role in regulating pLGIC function, yet the structural bases for specific pLGIC-lipid interactions remain poorly understood...

Descripción completa

Detalles Bibliográficos
Autores principales: Sridhar, Akshay, Lummis, Sarah C.R., Pasini, Diletta, Mehregan, Aujan, Brams, Marijke, Kambara, Kumiko, Bertrand, Daniel, Lindahl, Erik, Howard, Rebecca J., Ulens, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327344/
https://www.ncbi.nlm.nih.gov/pubmed/34157288
http://dx.doi.org/10.1016/j.jbc.2021.100899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327344/
https://www.ncbi.nlm.nih.gov/pubmed/34157288
http://dx.doi.org/10.1016/j.jbc.2021.100899

Ejemplares similares