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XMAP215 promotes microtubule catastrophe by disrupting the growing microtubule end

The GTP-tubulin cap is widely accepted to protect microtubules against catastrophe. The GTP-cap size is thought to increase with the microtubule growth rate, presumably endowing fast-growing microtubules with enhanced stability. It is unknown what GTP-cap properties permit frequent microtubule catas...

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Detalles Bibliográficos
Autores principales: Farmer, Veronica, Arpağ, Göker, Hall, Sarah L., Zanic, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327381/
https://www.ncbi.nlm.nih.gov/pubmed/34324632
http://dx.doi.org/10.1083/jcb.202012144