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PSPC1 is a new contextual determinant of aberrant subcellular translocation of oncogenes in tumor progression
Dysregulation of nucleocytoplasmic shuttling is commonly observed in cancers and emerging as a cancer hallmark for the development of anticancer therapeutic strategies. Despite its severe adverse effects, selinexor, a selective first-in-class inhibitor of the common nuclear export receptor XPO1, was...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327449/ https://www.ncbi.nlm.nih.gov/pubmed/34340703 http://dx.doi.org/10.1186/s12929-021-00753-3 |