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PSPC1 is a new contextual determinant of aberrant subcellular translocation of oncogenes in tumor progression

Dysregulation of nucleocytoplasmic shuttling is commonly observed in cancers and emerging as a cancer hallmark for the development of anticancer therapeutic strategies. Despite its severe adverse effects, selinexor, a selective first-in-class inhibitor of the common nuclear export receptor XPO1, was...

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Detalles Bibliográficos
Autores principales: Lang, Yaw-Dong, Jou, Yuh-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327449/
https://www.ncbi.nlm.nih.gov/pubmed/34340703
http://dx.doi.org/10.1186/s12929-021-00753-3