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Co-occurrence of cohesin complex and Ras signaling mutations during progression from myelodysplastic syndromes to secondary acute myeloid leukemia

Myelodysplastic syndromes (MDS) are hematological disorders at high risk of progression to secondary acute myeloid leukemia (sAML). However, the mutational dynamics and clonal evolution underlying disease progression are poorly understood at present. In order to elucidate the mutational dynamics of...

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Detalles Bibliográficos
Autores principales: Martín-Izquierdo, Marta, Abáigar, María, Hernández-Sánchez, Jesús M., Tamborero, David, López-Cadenas, Félix, Ramos, Fernando, Lumbreras, Eva, Madinaveitia-Ochoa, Andrés, Megido, Marta, Labrador, Jorge, Sánchez-Real, Javier, Olivier, Carmen, Dávila, Julio, Aguilar, Carlos, Rodríguez, Juan N., Martín-Nuñez, Guillermo, Santos-Mínguez, Sandra, Miguel-García, Cristina, Benito, Rocío, Díez-Campelo, María, Hernández-Rivas, Jesús M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327724/
https://www.ncbi.nlm.nih.gov/pubmed/32675227
http://dx.doi.org/10.3324/haematol.2020.248807