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BMP signaling is required for postnatal murine hematopoietic stem cell self-renewal

Life-long production of blood from hematopoietic stem cells (HSC) is a process of strict modulation. Intrinsic and extrinsic signals govern fate options like self-renewal – a cardinal feature of HSC. Bone morphogenetic proteins (BMP) have an established role in embryonic hematopoiesis, but less is k...

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Detalles Bibliográficos
Autores principales: Warsi, Sarah, Blank, Ulrika, Dahl, Maria, Grahn, Tan Hooi Min, Schmiderer, Ludwig, Andradottir, Silja, Karlsson, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327730/
https://www.ncbi.nlm.nih.gov/pubmed/32675226
http://dx.doi.org/10.3324/haematol.2019.236125