Fenofibrate reduces osteonecrosis without affecting antileukemic efficacy in dexamethasone-treated mice

Recent clinical trials in children with acute lymphoblastic leukemia (ALL) indicate that severe hypertriglyceridemia (>1000 mg/dL) during therapy is associated with an increased frequency of symptomatic osteonecrosis. Interventions to lower triglycerides have been considered, but there have been...

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Detalles Bibliográficos
Autores principales: Finch, Emily R., Payton, Monique A., Jenkins, David A., Cai, Xiangjun, Li, Lie, Karol, Seth E., Relling, Mary V., Janke, Laura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327737/
https://www.ncbi.nlm.nih.gov/pubmed/32675219
http://dx.doi.org/10.3324/haematol.2020.252767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327737/
https://www.ncbi.nlm.nih.gov/pubmed/32675219
http://dx.doi.org/10.3324/haematol.2020.252767

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