MYB bi-allelic targeting abrogates primitive clonogenic progenitors while the emergence of primitive blood cells is not affected

MYB is a key regulator of definitive hematopoiesis and it is dispensable for the development of primitive hematopoietic cells in vertebrates. In order to delineate definitive versus primitive hematopoiesis during differentiation of human embryonic stem cells, we have introduced reporters into the MY...

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Detalles Bibliográficos
Autores principales: Shah, Zahir, Philonenko, Elena S., Ramensky, Vasily, Fan, Chenyu, Wang, Cuihua, Ullah, Hanif, Zhang, Baoyun, Volchkov, Pavel, Samokhvalov, Igor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327747/
https://www.ncbi.nlm.nih.gov/pubmed/32732364
http://dx.doi.org/10.3324/haematol.2020.249193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327747/
https://www.ncbi.nlm.nih.gov/pubmed/32732364
http://dx.doi.org/10.3324/haematol.2020.249193

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