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Assessing conservation of alternative splicing with evolutionary splicing graphs

Understanding how protein function has evolved and diversified is of great importance for human genetics and medicine. Here, we tackle the problem of describing the whole transcript variability observed in several species by generalizing the definition of splicing graph. We provide a practical solut...

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Detalles Bibliográficos
Autores principales: Zea, Diego Javier, Laskina, Sofya, Baudin, Alexis, Richard, Hugues, Laine, Elodie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327911/
https://www.ncbi.nlm.nih.gov/pubmed/34266979
http://dx.doi.org/10.1101/gr.274696.120