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Evolution and genomic signatures of spontaneous somatic mutation in Drosophila intestinal stem cells

Spontaneous mutations can alter tissue dynamics and lead to cancer initiation. Although large-scale sequencing projects have illuminated processes that influence somatic mutation and subsequent tumor evolution, the mutational dynamics operating in the very early stages of cancer development are curr...

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Detalles Bibliográficos
Autores principales: Riddiford, Nick, Siudeja, Katarzyna, van den Beek, Marius, Boumard, Benjamin, Bardin, Allison J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327918/
https://www.ncbi.nlm.nih.gov/pubmed/34168010
http://dx.doi.org/10.1101/gr.268441.120