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Evolution and genomic signatures of spontaneous somatic mutation in Drosophila intestinal stem cells
Spontaneous mutations can alter tissue dynamics and lead to cancer initiation. Although large-scale sequencing projects have illuminated processes that influence somatic mutation and subsequent tumor evolution, the mutational dynamics operating in the very early stages of cancer development are curr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327918/ https://www.ncbi.nlm.nih.gov/pubmed/34168010 http://dx.doi.org/10.1101/gr.268441.120 |