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Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding

Eukaryotic cells employ three SMC (structural maintenance of chromosomes) complexes to control DNA folding and topology. The Smc5/6 complex plays roles in DNA repair and in preventing the accumulation of deleterious DNA junctions. To elucidate how specific features of Smc5/6 govern these functions,...

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Detalles Bibliográficos
Autores principales: Taschner, Michael, Basquin, Jérôme, Steigenberger, Barbara, Schäfer, Ingmar B, Soh, Young‐Min, Basquin, Claire, Lorentzen, Esben, Räschle, Markus, Scheltema, Richard A, Gruber, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327961/
https://www.ncbi.nlm.nih.gov/pubmed/34191293
http://dx.doi.org/10.15252/embj.2021107807