Chronic lithium treatment alters the excitatory/inhibitory balance of synaptic networks and reduces mGluR5–PKC signalling in mouse cortical neurons

BACKGROUND: Bipolar disorder is characterized by cyclical alternation between mania and depression, often comorbid with psychosis and suicide. Compared with other medications, the mood stabilizer lithium is the most effective treatment for the prevention of manic and depressive episodes. However, th...

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Detalles Bibliográficos
Autores principales: Khayachi, Anouar, Ase, Ariel, Liao, Calwing, Kamesh, Anusha, Kuhlmann, Naila, Schorova, Lenka, Chaumette, Boris, Dion, Patrick, Alda, Martin, Séguéla, Philippe, Rouleau, Guy, Milnerwood, Austen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: CMA Joule Inc. 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327978/
https://www.ncbi.nlm.nih.gov/pubmed/34077150
http://dx.doi.org/10.1503/jpn.200185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327978/
https://www.ncbi.nlm.nih.gov/pubmed/34077150
http://dx.doi.org/10.1503/jpn.200185

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