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Chronic lithium treatment alters the excitatory/inhibitory balance of synaptic networks and reduces mGluR5–PKC signalling in mouse cortical neurons
BACKGROUND: Bipolar disorder is characterized by cyclical alternation between mania and depression, often comorbid with psychosis and suicide. Compared with other medications, the mood stabilizer lithium is the most effective treatment for the prevention of manic and depressive episodes. However, th...
Autores principales: | Khayachi, Anouar, Ase, Ariel, Liao, Calwing, Kamesh, Anusha, Kuhlmann, Naila, Schorova, Lenka, Chaumette, Boris, Dion, Patrick, Alda, Martin, Séguéla, Philippe, Rouleau, Guy, Milnerwood, Austen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
CMA Joule Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327978/ https://www.ncbi.nlm.nih.gov/pubmed/34077150 http://dx.doi.org/10.1503/jpn.200185 |
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