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Intravital Imaging of Neocortical Heterotopia Reveals Aberrant Axonal Pathfinding and Myelination around Ectopic Neurons

Neocortical heterotopia consist of ectopic neuronal clusters that are frequently found in individuals with cognitive disability and epilepsy. However, their pathogenesis remains poorly understood due in part to a lack of tractable animal models. We have developed an inducible model of focal cortical...

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Detalles Bibliográficos
Autores principales: Li, Alice M, Hill, Robert A, Grutzendler, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328209/
https://www.ncbi.nlm.nih.gov/pubmed/33877363
http://dx.doi.org/10.1093/cercor/bhab090