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Asymmetric azidohydroxylation of styrene derivatives mediated by a biomimetic styrene monooxygenase enzymatic cascade

Enantioenriched azido alcohols are precursors for valuable chiral aziridines and 1,2-amino alcohols, however their chiral substituted analogues are difficult to access. We established a cascade for the asymmetric azidohydroxylation of styrene derivatives leading to chiral substituted 1,2-azido alcoh...

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Detalles Bibliográficos
Autores principales: Martínez-Montero, Lía, Tischler, Dirk, Süss, Philipp, Schallmey, Anett, Franssen, Maurice C. R., Hollmann, Frank, Paul, Caroline E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328376/
https://www.ncbi.nlm.nih.gov/pubmed/34381590
http://dx.doi.org/10.1039/d1cy00855b