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Structure-Function Relationships of Covalent and Non-Covalent BTK Inhibitors
Low-molecular weight chemical compounds have a longstanding history as drugs. Target specificity and binding efficiency represent major obstacles for small molecules to become clinically relevant. Protein kinases are attractive cellular targets; however, they are challenging because they present one...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328433/ https://www.ncbi.nlm.nih.gov/pubmed/34349760 http://dx.doi.org/10.3389/fimmu.2021.694853 |