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Antitumor Effect of Metformin in Combination with Binimetinib on Melanoma Cells

Cutaneous melanoma is a fatal disease for patients with distant metastasis. Metformin is the most widely used anti-diabetic drug, and proved to suppress cell proliferation and metastasis in diverse cancers including melanoma. We previously reported that MEK inhibitor trametinib increases the express...

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Detalles Bibliográficos
Autores principales: Lee, Eunsung, Kwon, Yongjae, Kim, Jiwon, Park, Deokbae, Lee, Youngki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Developmental Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328479/
https://www.ncbi.nlm.nih.gov/pubmed/34386644
http://dx.doi.org/10.12717/DR.2021.25.2.93