Homo-oligomerization of the human adenosine A(2A) receptor is driven by the intrinsically disordered C-terminus

G protein-coupled receptors (GPCRs) have long been shown to exist as oligomers with functional properties distinct from those of the monomeric counterparts, but the driving factors of oligomerization remain relatively unexplored. Herein, we focus on the human adenosine A(2A) receptor (A(2A)R), a mod...

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Detalles Bibliográficos
Autores principales: Nguyen, Khanh Dinh Quoc, Vigers, Michael, Sefah, Eric, Seppälä, Susanna, Hoover, Jennifer Paige, Schonenbach, Nicole Star, Mertz, Blake, O'Malley, Michelle Ann, Han, Songi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328514/
https://www.ncbi.nlm.nih.gov/pubmed/34269678
http://dx.doi.org/10.7554/eLife.66662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328514/
https://www.ncbi.nlm.nih.gov/pubmed/34269678
http://dx.doi.org/10.7554/eLife.66662

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