Synthesis, LC-MS/MS analysis, and biological evaluation of two vaccine candidates against ticks based on the antigenic P0 peptide from R. sanguineus linked to the p64K carrier protein from Neisseria meningitidis

A peptide from the P0 acidic ribosomal protein (pP0) of ticks conjugated to keyhole limpet hemocyanin from Megathura crenulata has shown to be effective against different tick species when used in host vaccination. Turning this peptide into a commercial anti-tick vaccine will depend on finding the a...

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Detalles Bibliográficos
Autores principales: González, Luis Javier, Encinosa Guzmán, Pedro E., Machado, Wendy, Pousa, Satomy, Leyva, Alejandro, Arguelles, Ana Laura Cano, Cabrera, Gleysin, Espinosa, Luis Ariel, Parra, Rubén, Hernández, Rachel, Soto, Yamil Bello, Ledesma, Frank L., Joglar, Marisdania, Guirola, Osmany, Kurt, Louise Ulrich, Carvalho, Paulo C., Cabrales, Ania, Garay, Hilda, Besada, Vladimir, Durán, Rosario, Takao, Toshifumi, Estrada, Mario Pablo, Rodríguez-Mallon, Alina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328535/
https://www.ncbi.nlm.nih.gov/pubmed/34341841
http://dx.doi.org/10.1007/s00216-021-03569-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328535/
https://www.ncbi.nlm.nih.gov/pubmed/34341841
http://dx.doi.org/10.1007/s00216-021-03569-0

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