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Histone H2Bub1 deubiquitylation is essential for mouse development, but does not regulate global RNA polymerase II transcription

Co-activator complexes dynamically deposit post-translational modifications (PTMs) on histones, or remove them, to regulate chromatin accessibility and/or to create/erase docking surfaces for proteins that recognize histone PTMs. SAGA (Spt-Ada-Gcn5 Acetyltransferase) is an evolutionary conserved mul...

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Detalles Bibliográficos
Autores principales: Wang, Fang, El-Saafin, Farrah, Ye, Tao, Stierle, Matthieu, Negroni, Luc, Durik, Matej, Fischer, Veronique, Devys, Didier, Vincent, Stéphane D., Tora, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329007/
https://www.ncbi.nlm.nih.gov/pubmed/33731875
http://dx.doi.org/10.1038/s41418-021-00759-2