Cargando…

Histone H2Bub1 deubiquitylation is essential for mouse development, but does not regulate global RNA polymerase II transcription

Co-activator complexes dynamically deposit post-translational modifications (PTMs) on histones, or remove them, to regulate chromatin accessibility and/or to create/erase docking surfaces for proteins that recognize histone PTMs. SAGA (Spt-Ada-Gcn5 Acetyltransferase) is an evolutionary conserved mul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Fang, El-Saafin, Farrah, Ye, Tao, Stierle, Matthieu, Negroni, Luc, Durik, Matej, Fischer, Veronique, Devys, Didier, Vincent, Stéphane D., Tora, László
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329007/ https://www.ncbi.nlm.nih.gov/pubmed/33731875 http://dx.doi.org/10.1038/s41418-021-00759-2

Ejemplares similares

SAGA-Dependent Histone H2Bub1 Deubiquitination Is Essential for Cellular Ubiquitin Balance during Embryonic Development
por: El-Saafin, Farrah, et al.
Publicado: (2022)

Homozygous TAF8 mutation in a patient with intellectual disability results in undetectable TAF8 protein, but preserved RNA polymerase II transcription
por: El-Saafin, Farrah, et al.
Publicado: (2018)

Global role for coactivator complexes in RNA polymerase II transcription
por: Fischer, Veronique, et al.
Publicado: (2018)

The related coactivator complexes SAGA and ATAC control embryonic stem cell self-renewal through acetyltransferase-independent mechanisms
por: Fischer, Veronique, et al.
Publicado: (2021)

The SAGA coactivator complex acts on the whole transcribed genome and is required for RNA polymerase II transcription
por: Bonnet, Jacques, et al.
Publicado: (2014)

SUPT3H-less SAGA coactivator can assemble and function without significantly perturbing RNA polymerase II transcription in mammalian cells
por: Fischer, Veronique, et al.
Publicado: (2022)

Lessons from genome-wide studies: an integrated definition of the coactivator function of histone acetyl transferases
por: Anamika, Krishanpal, et al.
Publicado: (2010)

SAGA is a general cofactor for RNA polymerase II transcription
por: Baptista, Tiago, et al.
Publicado: (2017)

Deubiquitylation of deubiquitylases
por: Haq, Saba, et al.
Publicado: (2017)

SAGA DUB-Ubp8 Deubiquitylates Centromeric Histone Variant Cse4
por: Canzonetta, Claudia, et al.
Publicado: (2015)

Deubiquitylating enzymes and disease
por: Singhal, Shweta, et al.
Publicado: (2008)

Usp7-dependent histone H3 deubiquitylation regulates maintenance of DNA methylation
por: Yamaguchi, Luna, et al.
Publicado: (2017)

Tip60 complex binds to active Pol II promoters and a subset of enhancers and co-regulates the c-Myc network in mouse embryonic stem cells
por: Ravens, Sarina, et al.
Publicado: (2015)

Ubiquitin-specific Peptidase 42 (USP42) Functions to Deubiquitylate Histones and Regulate Transcriptional Activity
por: Hock, Andreas K., et al.
Publicado: (2014)

A viral deubiquitylating enzyme targets viral RNA-dependent RNA polymerase and affects viral infectivity
por: Chenon, Mélanie, et al.
Publicado: (2012)

Deubiquitylating enzymes in neuronal health and disease
por: Amer-Sarsour, Fatima, et al.
Publicado: (2021)

Bub1 is essential for assembly of the functional inner centromere
por: Boyarchuk, Yekaterina, et al.
Publicado: (2007)

RNA Polymerase II Pausing Downstream of Core Histone Genes Is Different from Genes Producing Polyadenylated Transcripts
por: Anamika, Krishanpal, et al.
Publicado: (2012)

Expression and prognosis analyses of BUB1, BUB1B and BUB3 in human sarcoma
por: Long, Zeling, et al.
Publicado: (2021)

In Vivo Chromatin Organization of Mouse Rod Photoreceptors Correlates with Histone Modifications
por: Kizilyaprak, Caroline, et al.
Publicado: (2010)

Deubiquitylating Enzymes and DNA Damage Response Pathways
por: Jacq, Xavier, et al.
Publicado: (2013)

Deubiquitylating enzymes and their emerging role in plant biology
por: Isono, Erika, et al.
Publicado: (2014)

Deubiquitylating enzymes and drug discovery: emerging opportunities
por: Harrigan, Jeanine A., et al.
Publicado: (2017)

Histone H2Bub dynamics in the 5′ region of active genes are tightly linked to the UV-induced transcriptional response
por: Fanourgakis, Smaragda, et al.
Publicado: (2022)

Mof-associated complexes have overlapping and unique roles in regulating pluripotency in embryonic stem cells and during differentiation
por: Ravens, Sarina, et al.
Publicado: (2014)

Transcription and mRNA export machineries SAGA and TREX-2 maintain monoubiquitinated H2B balance required for DNA repair
por: Evangelista, Federica M., et al.
Publicado: (2018)

Co-translational assembly of mammalian nuclear multisubunit complexes
por: Kamenova, Ivanka, et al.
Publicado: (2019)

Riding the DUBway: regulation of protein trafficking by deubiquitylating enzymes
por: Millard, Susan M., et al.
Publicado: (2006)

Deubiquitylation Machinery Is Required for Embryonic Polarity in Caenorhabditis elegans
por: McCloskey, Richard J., et al.
Publicado: (2012)

USP4 Auto-Deubiquitylation Promotes Homologous Recombination
por: Wijnhoven, Paul, et al.
Publicado: (2015)

A Wolbachia Deubiquitylating Enzyme Induces Cytoplasmic Incompatibility
por: Beckmann, John F., et al.
Publicado: (2017)

USP10 deubiquitylates the histone variant H2A.Z and both are required for androgen receptor-mediated gene activation
por: Draker, Ryan, et al.
Publicado: (2011)

The Human Homologue of Bub3 Is Required for Kinetochore Localization of Bub1 and a Mad3/Bub1-related Protein Kinase
por: Taylor, Stephen S., et al.
Publicado: (1998)

Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity
por: Nishi, Ryotaro, et al.
Publicado: (2014)

The emerging role of deubiquitylating enzymes as therapeutic targets in cancer metabolism
por: Tu, Rongfu, et al.
Publicado: (2022)

The FOXM1/BUB1B signaling pathway is essential for the tumorigenicity and radioresistance of glioblastoma
por: Ma, Qing, et al.
Publicado: (2017)

EBNA1-Mediated Recruitment of a Histone H2B Deubiquitylating Complex to the Epstein-Barr Virus Latent Origin of DNA Replication
por: Sarkari, Feroz, et al.
Publicado: (2009)

Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans
por: Kim, Taekyung, et al.
Publicado: (2015)

Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint
por: Zhang, Gang, et al.
Publicado: (2015)

Differential requirement for Bub1 and Bub3 in regulation of meiotic versus mitotic chromosome segregation
por: Cairo, Gisela, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5uv2iovtsrla4bk2bcakbad22p