Computational design of SARS-CoV-2 peptide binders with better predicted binding affinities than human ACE2 receptor

SARS-CoV-2 is coronavirus causing COVID-19 pandemic. To enter human cells, receptor binding domain of S1 subunit of SARS-CoV-2 (SARS-CoV-2-RBD) binds to peptidase domain (PD) of angiotensin-converting enzyme 2 (ACE2) receptor. Employing peptides to inhibit binding between SARS-CoV-2-RBD and ACE2-PD...

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Detalles Bibliográficos
Autores principales: Sitthiyotha, Thassanai, Chunsrivirot, Surasak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329052/
https://www.ncbi.nlm.nih.gov/pubmed/34341401
http://dx.doi.org/10.1038/s41598-021-94873-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329052/
https://www.ncbi.nlm.nih.gov/pubmed/34341401
http://dx.doi.org/10.1038/s41598-021-94873-3

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